High-dose intravenous levetiracetam for acute seizure exacerbation in children with intractable epilepsy
نویسندگان
چکیده
منابع مشابه
High-dose intravenous levetiracetam for acute seizure exacerbation in children with intractable epilepsy.
We review our experience with high-dose intravenous levetiracetam (IV-LEV) for acute seizure exacerbations in nine children with medically intractable epilepsy. All children had acute repetitive seizures-while on chronic antiepileptic drugs-that either led to hospitalization (eight) or occurred during hospitalization (one), and received doses of IV-LEV of 150 mg/kg/day or greater, with a mean d...
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Epilepsy is a chronic medical condition that still poses a challenge in terms of treatment. There are a variety of anticonvulsants available today, but these do not prevent frequent hospital admissions and emergency room visits. Benzodiazepines, however, remain the first line treatment in acute seizure management. The approval of phenytoin, fosphenytoin, intravenous valproate, and rectal diazep...
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36 or encephalopathic process in some cases. Additional factors involved in the mechanism of the FS include a genetic susceptibility, age and maturation, and cytokine and immune response to infection [1]. The association of allergic rhinitis and FS in the present study was significantly higher in children 0.5 to 2 yrs of age (the age of susceptibility to FS), of male sex, and with frequent FS-r...
متن کاملintractable epilepsy in children
objective epilepsy is a common disorder affecting approximately 1% of the population. it is estimated that about 20- 30% of the patients become refractory to proper medical therapies. such cases are often termed intractable. intractable epilepsy (ie) is a serious condition in children, leading to significant impairment in quality of life, as well as behavioral and psychiatric problems. in this ...
متن کاملRetention rate of Levetiracetam in children with intractable epilepsy at 1 year
UNLABELLED Levetiracetam (LEV) is a novel antiepileptic drug (AED) that has recently obtained marketing authorisation for use in children. The purpose of this study was to assess the efficacy, tolerability and retention rate of LEV in children with refractory epilepsies. It is a retrospective multicentre observational study reporting the use of LEV in 200 children, aged 0.3-19 years (median 9-y...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2010
ISSN: 0013-9580,1528-1167
DOI: 10.1111/j.1528-1167.2010.02519.x